Medication Studies for Parasite Infections
I don’t know much about medication, but the subject has come up recently with several people and I thought that I’d look into medical studies again to help a few people out. Years ago, I had looked into this option but after my experience with medication, I decided to leave it alone.
The idea of “chemotherapy” treatment seems plausible for those who have tried basic medical treatment and it failed them. I have no doubts that more research is needed in this area before trying anything; medical supervision is best. Indeed, using pharmaceutical drugs for treating parasite infections is controversial, but it might be a hope for those who can use the therapy. While doing some research, I came across numerous studies regarding medical treatment for parasite infections and decided to share my findings.
Triple Drug Study
In this study Ivermectin, Albendazole/Albenza and Praziquantel were used on a large population in Zanzibar, Tanzania. The purpose of this study was to control Lymphatic Filariasis, Schistosomiasis (Flukes) and Soil-Transmitted Helminths. In reading this study few people had reactions; most were considered minor without requiring medical emergency intervention. Perhaps, more studies will be done in the future to corroborate the findings in this study.
Source: PLoS Research Article
Two Drug Combo
This was a study done in Iran for hydatid disease. Hydatid is a complicated infection caused by Echinococcosis.
Combination therapy with albendazole and praziquantel is effective in the treatment of hydatid cyst and can be used as an alternative to surgery in disseminated and nonoperable cases.
Spinal Hydatid Infection
Source: Iranian Hospital & Unversities
Long-term Medical Treatment
A small study was done in Greece where patients partook in a study of a drug combination for 3-6 months for hydatid cysts.
Brain Cysts - Albendazole or Praziquantel?
Source: Tropical Medicine & Hygiene
Source: Mahidol University, Thailand
Schistosomiasis & Pregnancy
Treating pregnant or lactating women with parasite infections is a difficult choice. Here are the concluding remarks:
This study, the first to examine the impact of praziquantel treatment during pregnancy, has shown that S mansoni antigen-specific antibody levels and praziquantel-induced boosts in the antibody levels are broadly low during pregnancy, but that this is not associated with any major reduction in the efficacy of praziquantel in the treatment of light to moderate intensity S. mansoni infections: a result that is reassuring from a public health perspective. Effects of pregnancy on the response to praziquantel among populations with higher S. mansoni infection intensities, and among women with S. haematobium or S. japonicum, and the long-term implications of these findings, particularly in relation to resistance to re-infection, remain to be explored.
Source: Biomed Central
This site has several abstracts with studies using Praziquantel on various parasite infections.
Each “Source” above has a link that directs you to available studies.
Before closing, I’d like to add that even though parasites might be the focus there are also co-infections that need to be addressed too. This is a fact and often overlooked.
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